On the curiosity spectrum, you have children on the one end, constantly asking questions about everything. On the other end, you have adults, who assume things are the way they are for a reason. Adults question very little, and so we tend to herd together, doing most things the same way as other people do them. The exceptions—adults who ask questions like children—are known as experimentalists. They question everything. Sometimes they come to agree that a popular approach has merit, but often they stumble on superior alternatives. Prepped by a vaccine, immune reinforcements will be marshaled to the fore much faster—within days of an invasion, sometimes much less. Adaptive cells called B cells, which produce antibodies, and T cells, which kill virus-infected cells, will have had time to study the pathogen’s features, and sharpen their weapons against it. While the guard dogs are pouncing, archers trained to recognize the virus will be shooting it down; the few microbes that make their way deeper inside will be gutted by sword-wielding assassins lurking in the shadows. “Each stage it has to get past takes a bigger chunk out” of the virus, Bhattacharya said. Even if a couple particles eke past every hurdle, their ranks are fewer, weaker, and less damaging. The road to breakthroughs is a series of Zen paradoxes. One of my favorites is the idea that pausing is the best way to move forward in the long run. The idea here is to take a beat—whether a minute or a day or a week—before you act. Smarter Faster Better: The Secrets of Being Productive in Life and Business by Charles Duhigg (2016)

Books | Adam Alter | Anatomy of a Breakthrough: How to Get

A psychologist and Nobel Prize winner summarizes and synthesizes the recent decades of research on intuition and systematic thinking. Creative Confidence: Unleashing the Creative Potential Within Us All by Tom and David Kelley (2013)

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El autor entrelaza ingeniosamente estudios científicos, anécdotas y entrevistas para explicar que las adversidades son parte de la vida y sentirse atascado es una característica más que un problema en el camino hacia el éxito. Afortunadamente, podemos superar el estancamiento y alcanzar nuestros objetivos más elevados implementando los ajustes y correcciones adecuados. Work Like Da Vinci: Gaining the Creative Advantage in Your Business and Career by Michael Gelb (2006) A groundbreaking guide to breaking free from the thoughts, habits, jobs , relationships, and even business models that prevent us from achieving our full potential.

The Atlantic What Happens When Vaccinated People Get COVID-19? - The Atlantic

These four attributes, deep domain expertise, skepticism, persistence and a collaborative approach don’t guarantee a breakthrough, but one rarely happens without them. When Jim Allison received a call from Dr. Jedd Wolchok, asking him to come to his office, he was puzzled at first. As a researcher, he rarely ventured into the clinical part of the hospital. Yet when he opened the door and saw his colleague sitting with a young woman whose emotion was clearly marked on her face, he immediately understood and tears began to fill his eyes.A brilliant detective story about the sources of human creativity. I loved it. * Malcolm Gladwell * The best examples of this come from elite athletes who sacrifice immediate performance for long-term dominance. For example, the greatest soccer player today (and perhaps ever), Lionel Messi, walks for the first few minutes of every game as he soothes his nerves and develops a sense of how the other 21 players on the field are behaving. He has never scored during the first two minutes of any game but has scored during every single other minute from three to ninety. That two-minute sacrifice pays dividends during the remaining eighty-eight-plus. “The idea here is to take a beat—whether a minute or a day or a week—before you act.” In art, music, writing, and business, the holy grail is an original idea—something revolutionary that no one’s considered before. The problem with ideas that appear revolutionary is that they’re almost never truly original. Instead, they’re what’s known as recombinations—the marriage of two old ideas to form something evolutionarily different. “When striving for new ideas, do as Dylan did by taking two or more good but disparate concepts, and seeing if you can merge them to form a novel recombination.” Allison was excited. He began to fly around the country presenting his results to all of the top pharmaceutical companies, but none showed interest. Over the years, they had spent billions on immunological approaches to cancer and weren’t ready to take another plunge. “It was depressing,” he told me. “I knew this discovery could make a difference, but nobody wanted to invest in it.”